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/ Каталог / Реагенты для научных исследований / Антитела / Антитела к регуляторам транскрипции
mtTFA Antibody (A-16) is a goat polyclonal IgG / Антитела поликлональные козьи IgG к mtTFA (A-16)
- mtTFA Antibody (A-16) is a goat polyclonal IgG provided at 200 µg/ml
- epitope mapping near the N-terminus of mtTFA of human origin
- recommended for detection of precursor and mature mtTFA of human and, to a lesser extent, mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
- blocking peptide, sc-30962 P
- See 1 citations for mtTFA Antibody (A-16)
mtTFA (mitochondrial transcription factor A), also known as mtTF1, TFAM, TCF6 (for transcription factor 6-like1), TCF6L2 and tsHMG, is a nuclear-encoded gene product that is imported into the mitochondria. mtTFA is required for many aspects of mitochondrial biogenesis including the replication and transcription of mitochondrial DNA (mtDNA). In mouse, testis-specific mtTFA is missing the mitochondria targeting sequence and is present in the nucleus rather than the mitochondria. This form of mtTFA is located primarily in the nuclei of elongated spermatids and may be involved in the regulation of gene expression of the haploid male genome. During mouse and human spermatogenesis there is a reduction of mtTFA protein levels and a reduction in mtDNA copy number. These features may provide one of the mechanisms by which paternal mtDNA transmission is prevented. mtTFA has been associated with mitochondrial disorder in humans characterized by ocular myopathy, exercise intolerance and muscle wasting. Информация для заказа:| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-30962 | | Цена (с НДС 20%): | | В корзину  |  Наименование: mtTFA Antibody (A-16) is a goat polyclonal IgG / Антитела поликлональные козьи IgG к mtTFA (A-16).
Примечание: SQ Category: Primary Antibodies,
Species: h > m, r,
Host Origin: human,
Applications: WB, IP, IF, ELISA,
UNSPSC: 12352203,
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