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α-Actin Antibody (1A4) is a mouse monoclonal IgG2a / Антитела моноклональные мышиные IgG2a к α-Actin (1A4)

• α-Actin Antibody (1A4) is a mouse monoclonal IgG_2a provided at 200 µg/ml
• raised against an N-terminal decapeptide of smooth muscle α-Actin of human origin
• recommended for detection of smooth muscle α-Actin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; non cross-reactive with Actin from fibroblasts (β-and γ-cytoplasmic), myocardium (α-myocardial) and striated muscle (α-sarcomeric)
• agarose conjugate for IP studies, sc-32251 AC, 500 µg/0.25 ml agarose
• See 27 citations for α-Actin Antibody (1A4)

All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. å-Actin expression is limited to various types of muscle, whereas ∫- and ©-Actin are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion. Rac regulates Actin filament accumulation at the plasma membrane. Cdc42 stimulates formation of filopodia.

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Область использования: Антитела к структурным протеинам Антитела к структурным протеинам для вестерн-блоттинга Антитела к структурным протеинам для иммунопреципитации Антитела к структурным протеинам для иммунофлуоресценции Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-32251
Цена (с НДС 20%):		В корзину
Наименование: α-Actin Antibody (1A4) is a mouse monoclonal IgG2a / Антитела моноклональные мышиные IgG2a к α-Actin (1A4). Примечание: SQ Category: Primary Antibodies, Species: m, r, h, Host Origin: human, Applications: WB, IP, IF, IHC(P), ELISA, UNSPSC: 12352203, datasheet