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Ep-CAM Antibody (EBA-1) is a mouse monoclonal IgG1 / Антитела моноклональные мышиные IgG к Ep-CAM (EBA-1)

• Ep-CAM Antibody (EBA-1) is a mouse monoclonal IgG₁ provided at 200 µg/ml
• raised against macromolecular aggregates containing breast carcinoma-associated mucin BCA-225 of human origin
• recommended for detection of Ep-CAM of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
• fluorescein (sc-66020 FITC) and phycoerythrin (sc-66020 PE) conjugates for FCM, 100 tests
• See 2 citations for Ep-CAM Antibody (EBA-1)

The epithelial cell adhesion molecule Ep-CAM, which is also designated tumor-associated calcium signal transducer 1 and MK-1, is a monomeric membrane glycoprotein that is expressed in most normal human epithelium and carcinomas. The human Ep-CAM gene encodes a 314 amino acid protein that is expressed as two forms, a major form and a minor form, which are reduced upon treatment with the amino-glycosylation inhibitor tunicamycin. Ep-CAM is overexpressed in a variety of carcinomas and is, therefore, a potential target for the visualization and therapy of human solid tumors. Ep-CAM contains an extracellular domain containing two epidermal growth factor-like repeats, followed by a cysteine poor region, which is necessary for the adhesion properties of the molecule.

Информация для заказа:

Область использования: Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-66020
Цена (с НДС 20%):		В корзину
Наименование: Ep-CAM Antibody (EBA-1) is a mouse monoclonal IgG1 / Антитела моноклональные мышиные IgG к Ep-CAM (EBA-1). Примечание: SQ Category: Primary Antibodies, Species: m, r, h, Host Origin: human, Applications: WB, IP, IF, IHC(P), FCM, UNSPSC: 12352203, datasheet