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Calponin 3 Antibody (A-2) is a mouse monoclonal IgG1

  • Calponin 3 Antibody (A-2) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against amino acids 275-329 mapping at the C-terminus of Calponin 3 of human and rat origin
  • recommended for detection of Calponin 3 of human origin by WB, IP, IF, IHC(P) and ELISA

Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.

Информация для заказа:

Область использования:Производство:Santa Cruz
Метод: 
Объем:200 мкг/мл 
Кат. номер:sc-271188
Цена (с НДС 20%): В корзину Добавить в корзину
Наименование: Calponin 3 Antibody (A-2) is a mouse monoclonal IgG1.
Примечание: SQ Category: Primary Antibodies,
Species: human,
Host Origin: human,
Applications: WB, IP, IF, IHC(P), ELISA,
UNSPSC: 12352203,
datasheet
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