| |
/ Каталог / Реагенты для научных исследований / Антитела / Антитела к структурным протеинам
Cytokeratin 18 Antibody (C-04) is a mouse monoclonal IgG1 / Антитела моноклональные мышиные IgG к Cytokeratin 18 (C-04)
- Cytokeratin 18 Antibody (C-04) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against cytoskeleton preparation of A-431 epidermal carcinoma cell line
- recommended for detection of Cytokeratin 18 of mouse, rat and human origin by WB, IP, IF and IHC(P); also reactive with additional species, including bovine, porcine and canine
- See 2 citations for Cytokeratin 18 Antibody (C-04)
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, Cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while Cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas. Cytokeratin 18 contains two major phosphorylation sites on Ser 33 and Ser 52. Phosphorylation of Ser 18 is essential for the association of Cytokeratin 18 with 14-3-3 proteins and is involved in keratin organization and distribution. Информация для заказа:| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-51582 | | Цена (с НДС 20%): | | В корзину  |  Наименование: Cytokeratin 18 Antibody (C-04) is a mouse monoclonal IgG1 / Антитела моноклональные мышиные IgG к Cytokeratin 18 (C-04) .
Примечание: SQ Category: Primary Antibodies,
Species: mouse, rat, human, bovine, porcine and canine,
Host Origin: human,
Applications: WB, IP, IF, IHC(P),
UNSPSC: 12352203,
datasheet |
|
