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TGFβ1 Antibody (TB21) is a mouse monoclonal IgG1

• TGFβ1 Antibody (TB21) is a mouse monoclonal IgG₁ provided at 100 µg/ml
• raised against TGFβ1 of human platelet origin
• recommended for detection of TGFβ1, both dimeric and monomeric natural forms under reducing and non reducing conditions of human and rat origin by WB, IP, IF, IHC(P) and FCM
• See 6 citations for TGFβ1 Antibody (TB21)

Transforming growth factor betas (TGF∫s) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFå. It is now realized that TGF∫s mediate many cell-cell interactions that occur during embryonic development. Three TGF∫s have been identified in mammals . TGF∫1, TGF∫2 and TGF∫3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF∫ requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF∫3 protein has approximately 80% identity to the mature region of both TGF∫1 and TGF∫2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity.

Информация для заказа:

Область использования: Антитела к факторам роста и гормонам Антитела к факторам роста и гормонам для иммуногистохимии Антитела к факторам роста и гормонам для проточной цитометрии Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	100 µg/ml
	Кат. номер:	sc-52893
Цена (с НДС 20%):		В корзину
Наименование: TGFβ1 Antibody (TB21) is a mouse monoclonal IgG1. Примечание: SQ Category: Primary Antibodies, Species: h, r, Host Origin: , Applications: WB, IP, IF, IHC(P), FCM, UNSPSC: 12352203, datasheet