BID Antibody (5C9) mouse monoclonal IgG1

BID Antibody (5C9) is a mouse monoclonal IgG₁ provided at 50µg/0.5 ml

raised against amino acids 61-118 of BID of human origin

recommended for detection of BID of mouse and human origin by WB and IP; also recommended for detection of bands at ~20, ~16 and ~14kDa corresponding to the cleaved forms of Bid in apoptotic cells

See 9 citations for BIDAntibody (5C9)

Members of the Bcl-2 family of proteins interact to regulate programmed cell death, or apoptosis. Various homodimers and heterodimers formed by proteins in this family can either promote or inhibit apoptosis. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect on certain hematopoietic cell lines following growth factor withdrawal. Additional apoptotic inhibitors in this family include A1, Bag-1, Bcl-w, Bcl-x and Mcl-1. Pro-apoptotic members of this family include Bax, Bad, Bak, Bik (NBK) and BID. BID contains a BH3 domain which allows it to dimerize with and counter the death repressor effects of Bcl-2. BID has also been shown to heterodimerize with Bcl-x and the death agonist Bax. BID is localized predominantly in the cytosol and is also present in membrane fractions. It is highly expressed in kidney and can also be detected in brain, spleen, liver, testis and lung.

Информация для заказа:

Область использования:

Производство:

Santa Cruz

Метод:

Объем:

50 µg/0.5 ml

Кат. номер:

sc-56025

Цена (с НДС 20%):

В корзину

Наименование: BID Antibody (5C9) mouse monoclonal IgG1.
Примечание: Видоспецифичность: человек.
Описание: мышиный моноклональный IgG1.
Приложение: вестерн блоттинг.
Доставка на голубом льду, Хранение при 4° C,
Подробное описание (на английском языке).