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S-100 α/β chain Antibody (B32.1) is a mouse monoclonal IgG1

• S-100 α/β chain Antibody (B32.1) is a mouse monoclonal IgG₁ provided at 100 µg/ml
• raised against S-100 of bovine origin
• recommended for detection of S-100 α and β chains of mouse, rat, human, bovine and monkey origin by IF and IHC(P); also reactive with additional species, including monkey, porcine and feline
• See 3 citations for S-100 α/β chain Antibody (B32.1)

The family of EF-hand type Ca2+-binding proteins includes calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 å and ∫, calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins), and the parvalbumin family members, including parvalbumin å and parvalbumin ∫ (also designated oncomodulin). The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression and differentiation. Research also indicates that the S-100 protein may function in the activation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly and inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100 å chain and S-100 ∫ chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of either two å chains, two ∫ chains or one å and one ∫ chain. S-100 localizes to the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. S-100 is also detected in almost all benign naevi, malignant melanocytic tumours and in Langerhans cells in the skin. Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 å and ∫ are present in a variety of other tissues, and calbindin is present in intestine and kidney.

Информация для заказа:

Область использования: Антитела к структурным протеинам Антитела к структурным протеинам для иммунофлуоресценции Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	100 µg/ml
	Кат. номер:	sc-58839
Цена (с НДС 20%):		В корзину
Наименование: S-100 α/β chain Antibody (B32.1) is a mouse monoclonal IgG1. Примечание: SQ Category: Primary Antibodies, Species: mouse, rat, human, bovine, monkey, porcine and feline, Host Origin: bovine, Applications: IF, IHC(P), UNSPSC: 12352203, datasheet