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TGFβ2 (V) Antibody is a rabbit polyclonal IgG

  • TGFβ2 (V) Antibody is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of TGFβ2 of human origin
  • recommended for detection of TGFβ2 and, to a lesser extent, TGFβ3 of mouse, rat, human, porcine and Xenopus origin by WB, IP, IF, IHC(P) and ELISA; non-cross reactive with TGFβ1; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-90 P
  • agarose conjugate for IP studies, sc-90 AC, 500 µg/0.25 ml agarose
  • also provided azide-free for neutralization studies, sc-90 L, 200 µg/0.1 ml
  • See 56 citations for TGFβ2 (V) Antibody

 

Transforming growth factor betas (TGFβs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFα. It is now realized that TGFβs mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGFβ1, TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFβ requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFβ3 protein has approximately 80% identity to the mature region of both TGFβ1 and TGFβ2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity.

Информация для заказа:

Область использования:Производство:Santa Cruz
Метод: 
Объем:200 мкг/мл 
Кат. номер:sc-90
Цена (с НДС 20%): В корзину Добавить в корзину
TGFβ2 (V) Antibody is a rabbit polyclonal IgGНаименование: TGFβ2 (V) Antibody is a rabbit polyclonal IgG.
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, IHC(P), ELISA,
UNSPSC: 12352203,
datasheet
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