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BDNF Antibody (N-20) is a rabbit polyclonal IgG / Антитела поликлональные кроличьи IgG к BDNF (N-20)

• BDNF Antibody (N-20) is a rabbit polyclonal IgG provided at 200 µg/ml
• epitope mapping within an internal region of BDNF of human origin
• recommended for detection of precursor and mature BDNF and, to a lesser extent, NGF of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine, avian and feline
• blocking peptide, sc-546 P
• See 125 citations for BDNF Antibody (N-20)

Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). These various neurotrophins stimulate the in vitro survival of distinct, but partially overlapping, populations of neurons. The cell surface receptors through which neurotrophins mediate their activity have been identified. For instance, the Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds both BDNF and NT-4 equally well, and binds NT-3 to a lesser extent, while the Trk C receptor only binds NT-3.

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Область использования: Антитела для исследований в области нейробиологии для вестерн-блоттинга Антитела для исследований в области нейробиологии для иммунопреципитации Антитела для исследований в области нейробиологии для иммунофлуоресценции Нейробиология Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-546
Цена (с НДС 20%):		В корзину
Наименование: BDNF Antibody (N-20) is a rabbit polyclonal IgG / Антитела поликлональные кроличьи IgG к BDNF (N-20). Примечание: SQ Category: Primary Antibodies, Species: m, r, h, Host Origin: human, Applications: WB, IP, IF, IHC(P), ELISA, UNSPSC: 12352203, datasheet