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NFκB p50 (D-17) / Козьи поликлональные антитела к NFκB p50 (D-17)

• goat polyclonal IgG, 200 µg/ml
• epitope mapping at the N-terminus of NFκB p50 of mouse origin
• recommended for detection of NFκB p50 and p105 of mouse and rat origin by WB, IP, IF and ELISA
• blocking peptide, sc-1192 P
• TransCruz reagent for Gel Supershift and ChIP applications, sc-1192 X, 200 µg/0.1 ml

Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor NF˚B (p50 and p65) and the Drosophila maternal morphagen, dorsal. These proteins share sequence homology over a region of 300 amino acids at their NH2-terminus, the region that contains their DNA binding and dimerization domains. The DNA binding activity of NF˚B is activated and rapidly transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins have been described. These proteins, designated p105 and p100, are highly related but map on different chromosomes. The p105 (p110) precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated PdI, binds to p50 and regulates its activity.

Информация для заказа:

Область использования: Антитела к регуляторам транскрипции Антитела к регуляторам транскрипции для вестерн-блоттинга Антитела к регуляторам транскрипции для иммунопреципитации Антитела к регуляторам транскрипции для иммунофлуоресценции Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-1192
Цена (с НДС 20%):		В корзину
Наименование: NFκB p50 (D-17) / Козьи поликлональные антитела к NFκB p50 (D-17). Примечание: SQ Category: Primary Antibodies, Species: m, r, Host Origin: mouse, Applications: WB, IP, IF, ELISA, UNSPSC: 12352203, datasheet