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WASP Antibody (D-1)PE is a mouse monoclonal IgG1
- WASP Antibody (D-1) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against amino acids 1-250 of WASP of human origin
- recommended for detection of WASP of human origin by WB, IP, IF, IHC(P), FCM and ELISA
- phycoerythrin conjugate for intracellular FCM, sc-5300 PE, 100 tests
- Alexa Fluor® 405 (sc-5300 AF405), Alexa Fluor® 488 (sc-5300 AF488) and Alexa Fluor® 647 (sc-5300 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
- See 18 citations for WASP Antibody (D-1)
The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42. Информация для заказа:| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 100 tests in 2ml | | Кат. номер: | sc-5300 PE | | Цена (с НДС 20%): | | В корзину  |  Наименование: WASP Antibody (D-1)PE is a mouse monoclonal IgG1 .
Примечание: SQ Category: Primary Antibody Conjugates,
Species: ,
Host Origin: ,
Applications: WB, IP, IF, IHC(P), FCM, ELISA,
UNSPSC: 12352203,
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