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AFP Antibody (C-19) is a goat polyclonal IgG / Антитела поликлональные козьи IgG к AFP (C-19)

  • AFP Antibody (C-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of AFP of human origin
  • recommended for detection of alpha fetoprotein of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
  • blocking peptide, sc-8108 P
  • fluorescein (sc-8108 FITC) and rhodamine (sc-8108 TRITC) conjugates for immunofluorescence, 200 µg/ml
  • HRP conjugate, sc-8108 HRP, 200 µg/ml
  • See 18 citations for AFP Antibody (C-19)

å-fetoprotein (AFP) is expressed in fetal liver at varying levels throughout development and is present only in trace amounts in normal adult tissues. AFP can be detected at abnormally high concentrations in hepatocellular carcinomas as well as in the plasma and ascitic fluid of adults with hepatoma. High AFP concentrations have been correlated with tumor cell growth, indicating that AFP can serve as a tumor marker. AFP binds copper, nickel and fatty acids, and in some cases may bind serum albumin or estrogen. It has been demonstrated that the AFP promoter is a target for NF-1 (nuclear factor-1), HNF-1 (hepatocyte nuclear factor-1) and C/EBP transcription factors. While HNF-1 binding to the AFP promoter results in AFP expression, NF-1 binding results in a decrease in AFP promoter activity.

Информация для заказа:

Область использования:Производство:Santa Cruz
Метод: 
Объем:200 мкг/мл 
Кат. номер:sc-8108
Цена (с НДС 20%): В корзину Добавить в корзину
AFP Antibody (C-19) is a goat polyclonal IgG  / Антитела поликлональные козьи IgG к AFP (C-19)Наименование: AFP Antibody (C-19) is a goat polyclonal IgG / Антитела поликлональные козьи IgG к AFP (C-19).
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, ELISA,
UNSPSC: 12352203,
datasheet
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