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/ Каталог / Реагенты для научных исследований / Антитела / Антитела к регуляторам транскрипции
myogenin (F5D) / Мышиные моноклональные антитела к миогенин (F5D)
- myogenin Antibody (F5D) is a mouse monoclonal IgG1 provided at 200 µg/ml
- epitope mapping within amino acids 138-158 of myogenin of rat origin
- recommended for detection of myogenin of mouse, rat and human origin by WB, IP, IF and IHC(P)
- TransCruz reagent for Gel Supershift and ChIP applications, myogenin (F5D) X: sc-12732 X, 200 µg/0.1 ml
- agarose conjugate for IP studies, myogenin (F5D) AC: sc-12732 AC, 500 µg/0.25 ml agarose
- See 86 citations for myogeninAntibody (F5D)
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Информация для заказа:Область использования: | Производство: | Santa Cruz | Метод: | | Объем: | 200 мкг/мл | Кат. номер: | sc-12732 | Цена (с НДС 20%): | | В корзину | Наименование: myogenin (F5D) / Мышиные моноклональные антитела к миогенин (F5D). Примечание: SQ Category: Primary Antibodies, Species: m, r, h, Host Origin: rat, Applications: WB, IF, IHC(P), UNSPSC: 12352203, datasheet |
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