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myogenin (F5D) / Мышиные моноклональные антитела к миогенин (F5D)

  • myogenin Antibody (F5D) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • epitope mapping within amino acids 138-158 of myogenin of rat origin
  • recommended for detection of myogenin of mouse, rat and human origin by WB, IP, IF and IHC(P)
  • TransCruz reagent for Gel Supershift and ChIP applications, myogenin (F5D) X: sc-12732 X, 200 µg/0.1 ml
  • agarose conjugate for IP studies, myogenin (F5D) AC: sc-12732 AC, 500 µg/0.25 ml agarose
  • See 86 citations for myogeninAntibody (F5D)
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes.

Информация для заказа:

Область использования:Производство:Santa Cruz
Метод: 
Объем:200 мкг/мл 
Кат. номер:sc-12732
Цена (с НДС 20%): В корзину Добавить в корзину
myogenin (F5D) / Мышиные моноклональные антитела к миогенин (F5D)Наименование: myogenin (F5D) / Мышиные моноклональные антитела к миогенин (F5D).
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: rat,
Applications: WB, IF, IHC(P),
UNSPSC: 12352203,
datasheet
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