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Mucin 6 (S-20) / Козьи поликлональные антитела к Муцин 6 (S-20)

• goat polyclonal IgG, 200 µg/ml
• epitope mapping within an internal region of Mucin 6 of human origin
• recommended for detection of Mucin 6 of human origin by WB, IF and ELISA
• blocking peptide, sc-16915 P

Mucin 6 (also designated MUC 6 and gastric mucin) is a large glycoprotein that plays a major role in the protection of the gastrointestinal tract. Mucin 6 carries GlcNAcå1-->4Gal∫-->R structures, indicating that å1, 4-N-acetylglucosaminyltransferase is important to the formation of the mucous glycoproteins in vivo. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 apomucin is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation. Mucin 6 mRNA is expressed transiently in the nephrogenic zone of the kidney in the early mid-trimester of development, and Mucin 6 glycoprotein is expressed in the epithelium of ureteric buds and collecting ducts, but absent from adult kidney. Proliferating bile ductular cells express Mucin 6 apomucin in diseased liver, especially in chronic viral hepatitis with active necroinflammation, suggesting that this secreted mucin acts as a cytoprotective agent and represents a phenotype of reactive biliary epithelium in chronic viral hepatitis.

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Область использования: Антитела к белкам неспецифической адгезии клеток Антитела к белкам неспецифической адгезии клеток для вестерн-блоттинга Антитела к белкам неспецифической адгезии клеток для иммунофлуоресценции Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-16915
Цена (с НДС 20%):		В корзину
Наименование: Mucin 6 (S-20) / Козьи поликлональные антитела к Муцин 6 (S-20). Примечание: SQ Category: Primary Antibodies, Species: human, Host Origin: human, Applications: WB, IF, ELISA, UNSPSC: 12352203, datasheet