| |
/ Каталог / Реагенты для научных исследований / Антитела / Антитела к киназам и фосфатазам
GRK 2 Antibody (C-15) is a rabbit polyclonal IgG / Антитела поликлональные кроличьи IgG к GRK 2 (C-15)
- GRK 2 Antibody (C-15) is a rabbit polyclonal IgG provided at 200 µg/ml
- epitope mapping at the C-terminus of GRK 2 of human origin
- recommended for detection of GRK 2 of mouse, rat, human and bovine origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, and porcine
- blocking peptide, sc-562 P
- agarose conjugate for IP studies, sc-562 AC, 500 µg/0.25 ml agarose
- See 63 citations for GRK 2 Antibody (C-15)
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonist-mediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first class is comprised of the second messenger-regulated kinases, such as c-AMP dependent protein kinase A and protein kinase C. The second class includes the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1), two forms of beta-adrenergic receptor kinase: GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state. Информация для заказа:| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-562 | | Цена (с НДС 20%): | | В корзину  |  Наименование: GRK 2 Antibody (C-15) is a rabbit polyclonal IgG / Антитела поликлональные кроличьи IgG к GRK 2 (C-15).
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,,
Host Origin: human,
Applications: WB, IP, IF, ELISA,
UNSPSC: 12352203,
datasheet |
|
