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Anti-NOS2 Antibody (C-11) / Антитело к NOS2 (C-11) / Антитела моноклональные мышиные IgG1 к NOS2 (C-11)

• NOS2 Antibody (C-11) is a mouse monoclonal IgG₁ provided at 200 µg/ml
• specific for an epitope mapping between amino acids 1120-1145 near the C-terminus of NOS2 of mouse origin
• recommended for detection of NOS2 (iNOS) of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA
• blocking peptide, sc-7271 P
• fluorescein (sc-7271 FITC) and rhodamine (sc-7271 TRITC) conjugates for immunofluorescence, 200 µg/ml
• agarose conjugate for IP studies, sc-7271 AC, 500 µg/0.25 ml agarose
• Alexa Fluor®405 (sc-7271 AF405), Alexa Fluor® 488 (sc-7271 AF488) and Alexa Fluor® 647 (sc-7271 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
• See 86 citations for NOS2 Antibody (C-11)

Nitric oxide (NO) has a broad range of biological activities and has been implicated in signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells. The inducible form of NOS, NOS2 (also designated iNOS), is Ca2+-independent and is expressed in a broad range of cell types.

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Область использования: Антитела к белкам синтеза и распада Антитела к белкам синтеза и распада для вестерн-блоттинга Антитела к белкам синтеза и распада для иммунопреципитации Антитела к белкам синтеза и распада для иммунофлуоресценции Антитела к белкам синтеза и распада для проточной цитометрии Первичные антитела и конъюгаты Реагенты SantaCruz	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг
	Кат. номер:	sc-7271
Цена (с НДС 20%):		В корзину
Наименование: Anti-NOS2 Antibody (C-11) / Антитело к NOS2 (C-11) / Антитела моноклональные мышиные IgG1 к NOS2 (C-11). Примечание: SQ Category: Primary Antibodies, Species: m, r, h, Host Origin: mouse, Applications: WB, IP, IF, IHC(P), FCM, ELISA, UNSPSC: 12352203, datasheet