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/ Каталог / Реагенты для научных исследований / Антитела / Антитела к киназам и фосфатазам
GRK 1 Antibody (G-8) is a mouse monoclonal IgG1 / Антитела моноклональные мышиные IgG1 к GRK 1 (G-8)
- GRK 1 Antibody (G-8) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against full-length GRK 1 of human origin with epitope mapping at the C-terminus
- recommended for detection of GRK 1 of mouse, rat, human bovine and avian by WB, IP, IF and ELISA
- agarose conjugate for IP studies, sc-8004 AC, 500 µg/0.25 ml agarose
- See 4 citations for GRK 1 Antibody (G-8)
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonist-mediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first class is comprised of the second messenger-regulated kinases, such as c-AMP dependent protein kinase A and protein kinase C. The second class includes the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1å and ∫); two forms of ∫-adrenergic receptor kinase: GRK 2 (∫ARK, ∫ARK1) and GRK 3 (∫ARK2); IT-11 (GRK 4); GRK 5; GRK 6; and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state. Информация для заказа:| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-8004 | | Цена (с НДС 20%): | | В корзину  |  Наименование: GRK 1 Antibody (G-8) is a mouse monoclonal IgG1 / Антитела моноклональные мышиные IgG1 к GRK 1 (G-8).
Примечание: SQ Category: Primary Antibodies,
Species: mouse, rat, human, bovine and avian,
Host Origin: human,
Applications: WB, IP, IF, ELISA,
UNSPSC: 12352203,
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