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MMP-9 (2C3) / MMP-9 Antibody (2C3) is a mouse monoclonal IgG1

• MMP-9 Antibody (2C3) is a mouse monoclonal IgG₁ provided at 200 µg/ml
• raised against amino acids 603-614 of MMP-9 of human origin
• recommended for detection of MMP-9 of human origin by WB, IP, IF and IHC(P)
• agarose conjugate for IP studies, MMP-9 (2C3) AC: sc-21733 AC, 500 µg/0.25 ml agarose
• See 33 citations for MMP-9 Antibody (2C3)

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc (3). MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.

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Область использования: Антитела к белкам синтеза и распада Антитела к белкам синтеза и распада для вестерн-блоттинга Антитела к белкам синтеза и распада для иммуногистохимии Антитела к белкам синтеза и распада для иммунопреципитации Антитела к белкам синтеза и распада для иммунофлуоресценции Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-21733
Цена (с НДС 20%):		В корзину
Наименование: MMP-9 (2C3) / MMP-9 Antibody (2C3) is a mouse monoclonal IgG1. Примечание: SQ Category: Primary Antibodies, Species: human, Host Origin: human, Applications: WB, IP, IF, IHC(P), UNSPSC: 12352203, datasheet